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Cytokines are molecules secreted by the immune system that trigger inflammation

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Endocr Pract (2012) 18(4):4727

While nNOS and eNOS-mediated production of NO is low-output and is important for normal physiological functions, the production of NO by iNOS is classified as high-output and is involved in infection and inflammation (MacMicking et al., 1997)

The inclusion of additional enhancers like Vitamin C